Male infertility refers to a male's inability to cause pregnancy in a fertile female. In humans it accounts for 40–50% of infertility. Male infertility is commonly due to deficiencies in the semen, and semen quality is used as a surrogate measure of male fecundity. Deficiencies in the semen are the cause of the following diseases.
Asthenozoospermia:
.Asthenozoospermia is an infertility condition in men where a man produces low motility
sperm. Motility is the ability of the sperm to travel forward rapidly and in a straight line. It
is an essential requirement of a natural conception. Reduced sperm motility reduces the
chances of the sperm being successfully fertilized in the female reproductive tract.
Asthenozoospermia intercepts the production of cell energy that helps the sperm swim
easily to a woman in the uterus, causing infertility. Sperm motility plays an extremely
important role in the design process. The ejaculated sperm must be swift to penetrate
the cervical mucus, swim in the uterus, and eventually penetrate the layers of the egg to
fertilize the ovum.
Causes:
Causes of complete asthenozoospermia include metabolic defects, ultrastructural
disorders of flagellum sperm, and necrozoospermia.
Azoospermia:
Azoospermia is a lack of sperm in seminal fluid. In humans, azoospermia affects about
1% of the male population.
Types:
1: Pre-testicular Azoospermia (non-obstructive): In pre-testicular azoospermia, the
testicles and genital tract are normal but are not appropriately stimulated by the
hormonal system to produce sperm. The defects in the hypothalamus and/or pituitary
gland, both of which are located in the brain, cause a hormonal imbalance that prevents
normal testicles from being stimulated to produce sperm.
Causes : Pretesticular azoospermia is associated with poor nutrition, the use of certain
medications (e.g., particular chemotherapies, narcotics), pituitary tumors, trauma, and low
testosterone (hypogonadism).
2: Testicular Azoospermia: Testicular azoospermia indicates that there is a sperm
production defect in the testicles themselves. The disorder may be congenital (i.e. the
problem is present at birth) or acquired. The production of sperm may be completely absent
or may involve arrest during the early or late stage of sperm maturation.
Causes:
Testicular azoospermia causes can be divided into two parts these are:
Congential causes:
Congenital causes of testicular azoospermia include conditions such as undescended
testicles , Klinefelter’s syndrome, and Sertoli-cell-only syndrome. A variety of genetic
abnormalities may also impair sperm production. The two most common categories of
genetic errors causing testicular azoospermia are:
Acquired causes:
Testicular azoospermia may be acquired as a result of infection (e.g. mumps orchitis,
malaria), exposure to pesticides and chemicals, testicular trauma, cancer and cancer
treatment, or radiation therapy. Azoospermia may also be associated with varicocele (an
abnormal enlargement of the veins draining the testicle) which may cause testicular
hyperthermia (overheating).
3: Post testicular Azoospermia: In post-testicular azoospermia, also called obstructive
azoospermia, sperm is produced by normal testicles but is not ejaculated due to an
obstruction of the genital tract.
Causes:
Hyperspermia:
Hyperspermia is a condition that causes a person to produce a large amount of semen,
a fluid that contains sperm. Hyperspermia is a relatively rare condition compared with
other issues that affect sperm. It does not cause any physical changes or health
conditions. However, it may reduce fertility. Hyperspermia is a disease that occurs when
a person produces more semen than normal. Doctors usually describe this quantity as
more than 5.5 milliliters ( ml) per ejaculation, although some have a slightly higher limit
of 6 ml per ejaculation.
Causes: The exact cause of hyperspermia is yet to be known. However, it is believed to
be caused due to the below-given factors:
Hypospermia:
Hypospermia is male diagnosis characterized by reduced semen volume, Semen
volume lower than 1,5 ml is classified as hypospermia. It is the logical opposite
of hyperspermia. It should not be confused with oligospermia, which means
low sperm count..
Causes: Hypospermia can be a result of various other conditions or abnormalities.
Trauma associated with exercise or surgery is associated with causing complications in
the male reproductive system. Lifestyle habits and congenital defects too are factors.
Here are the main causes of hypospermia
Oligospermia:
Terms oligospermia, oligozoospermia, and low sperm count refer to semen with a low
concentration of sperm. A healthy sperm amount is often necessary for fertility. The
World Health Organization (WHO) classifies sperm counts at or above 15 million sperm
per milliliter (mL) of semen as average. Anything below that is considered low and is
diagnosed as oligospermia.
Causes:
Varicocele:
Enlarged veins in a man’s scrotum can disrupt blood flow to the testicles. This can
cause the temperature in the testicles to increase. Any increase in temperature can
negatively impact sperm production. About 40 percent of men with low sperm numbers
or low sperm quality count have this common issue.
Viruses like sexually transmitted infections can reduce the sperm amount in semen.
Ejaculation issues:
While many men with oligospermia have typical ejaculations, some ejaculation
problems may reduce sperm count. Retrograde ejaculation is one such issue. This
occurs when semen enters the bladder instead of leaving from the tip of the penis.
Other things that may interfere with typical ejaculation include:
Medications:
Beta blockers, antibiotics, and blood pressure medications may cause ejaculation
problems and reduce sperm count.
Hormone issues
The brain and the testicles produce several hormones that are responsible for
ejaculation and sperm production. An imbalance in any of these hormones may lower
sperm count numbers.
Exposure to chemicals and metals
Pesticides, cleaning agents, and painting materials are a few of the chemicals that can
reduce sperm count. Exposure to heavy metals, such as lead, can cause this problem,
too.
Overheating testicles
Sitting frequently, placing laptops over your genitals, and wearing tight clothing may all
contribute to overheating. An increase in temperature around the testicles may
temporarily reduce sperm production. It’s unclear what long-term complications may
occur.
Drug and alcohol use
The use of some substances, including marijuana and cocaine, may reduce sperm
counts. Excessive drinking can do the same. Men who smoke cigarettes may have
lower sperm counts than men who do not smoke.
Weight problems
Being overweight or obese increases your risk for low sperm counts in several ways.
Excess weight can directly reduce how much sperm your body can make. Weight
problems may also interfere with hormone production.
Necrospermia:
Necrospermia (or necrozoospermia) is a condition in which there is a low percentage of live
sperm and a very high percentage of immotile sperm in semen.
There are two types of necrozoospermia. These are as follow:
1: Incomplete necrozoospermia is when many but not all of the sperm in a semen sample are
dead. Typically, when less than 45%, but more than 5%, are viable.
2: Complete necrozoospermia is when all the sperm in a semen sample are dead.
Causes:
It’s not entirely clear what causes necrozoospermia. Because it is so rare, there are a
lot of unknowns.
Some possible causes and theories behind necrozoospermia include...4
Teratospermia:
Teratospermia, also referred to as teratozoospermia, is defined as abnormal sperm
morphology (shape), caused by either defect in the head, midpiece and/or tail. It is a
disorder in which males produce wonky-looking sperms. This, in turn, affects their
chances of fertilizing the eggs.
Causes:
The causes of teratospermia are not clearly defined and are difficult to determine.
However, physiological stress is said to have an effect on the morphology of the
sperms. The following factors are suggested to be the most common causes: